BYSTOLIC PI PDF

BYSTOLIC PI PDF

Learn about prescribing BYSTOLIC® (nebivolol), a beta blocker indicated for the treatment of hypertension. See full Prescribing & Safety Information. BYSTOLIC is a beta-adrenergic blocking agent indicated for . BYSTOLIC is available as tablets for oral administration containing nebivolol hydrochloride. Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in Bystolic is contraindicated in patients with severe bradycardia, heart block with other risks as described in the Adverse Reactions section of its PI.

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Concomitant use can increase the risk of bradycardia.

Nebivolol – Wikipedia

For questions about the program, including savings on mail-order prescriptions, please call 1. When you redeem this card, you certify that you have not submitted and will not submit a claim for reimbursement under any federal, state, or other government programs for this prescription. Patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine while taking beta blockers.

Both digitalis glycosides and beta blockers slow atrioventricular conduction and decrease heart rate. Beta blockers can precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular disease. Maximum savings limits apply; patient out-of-pocket expense will vary. Patients may not use this offer if they are Medicare-eligible and enrolled in an employer-sponsored health plan or prescription drug benefit program for retirees.

Severe exacerbation of angina, myocardial infarction, and ventricular arrhythmias have been reported following the abrupt discontinuation of therapy with beta blockers.

Caution patients without overt coronary artery disease against interruption or abrupt discontinuation of therapy. In patients with known or suspected pheochromocytoma, initiate an alpha blocker prior to the use of any beta blocker. Other possible side effects include masking hiding the symptoms of low blood sugar and hyperthyroidism overactive thyroidespecially a fast heartbeat.

If beta-blocking therapy is withdrawn prior to major surgery, the impaired ability of bystllic heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures. Additionally, bysrolic in restarting and maintaining the heartbeat has been reported with beta blockers.

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C Risk not ruled out. What lifestyle changes can help lower your blood pressure?

BYSTOLIC Formulary Coverage Tool

Please see full Prescribing Information. Caution patients without overt coronary artery disease against interruption or abrupt discontinuation of therapy. You will receive no benefit from such a donation. However, such patients may be subject to protracted severe hypotension. Because of significant negative inotropic and chronotropic effects in patients treated with beta blockers and calcium channel blockers of the verapamil and diltiazem type, monitor the ECG and blood pressure of patients treated concomitantly with these agents.

This card is not transferable. Metabolism of nebivolol is decreased in patients with moderate hepatic impairment. Nebivolol is unique as a beta-blocker.

High Blood Pressure Treatment | BYSTOLIC® (nebivolol)

This offer is not valid for cash-paying patients. In general, patients with bronchospastic diseases should not receive beta blockers. Beta blockers may mask clinical signs of hyperthyroidism, such as tachycardia. Please enter your email address.

For questions about the program, including savings on mail-order prescriptions, please call 1. Patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine while taking beta blockers. Because beta blocker withdrawal has been associated with an increased risk of MI and chest pain, patients already on beta blockers should generally continue pk throughout the perioperative period if undergoing major surgery.

In a placebo-controlled trial of oi BYSTOLIC, placebo over 70 years of age with chronic heart failure receiving a maximum dose of 10 mg per day for a median of 20 months, no worsening of heart failure was reported with nebivolol compared to bysolic.

Discover if BYSTOLIC can help lower your high blood pressure

Nebivolol bysrolic already registered and successfully marketed in more than 50 countries, including the United States where it is marketed under the brand name Bystolic from Mylan Laboratories and Forest Laboratories. Due to enzymatic inhibition, fluvoxamine increases the exposure to nebivolol and its active hydroxylated metabolite 4-OH-nebivolol in healthy volunteers.

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Metabolism of nebivolol is decreased in patients with moderate hepatic impairment. This card has no cash value and may not be used in combination with any other discount, coupon, rebate, free trial, or similar offer for the specified prescription.

Concomitant use can increase the risk of bradycardia.

If BYSTOLIC is to be continued perioperatively, monitor patients closely when anesthetic agents which depress myocardial function, such as ether, cyclopropane, and trichloroethylene are used. Mended Hearts is an independent c 3 organization; to learn more visit MendedHearts. If beta-blocking therapy bysgolic withdrawn prior to major surgery, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.

Both digitalis glycosides and beta blockers slow atrioventricular conduction and decrease heart rate. The most common side effects people taking BYSTOLIC report are headache, fatigue tirednessdizziness if you feel dizzy, sit or lie down and tell your doctor right awaydiarrhea, nausea, insomnia difficulty falling or staying asleepchest bysto,ic, bradycardia slow heartbeatdyspnea shortness of breathrash, and peripheral edema leg swelling due to fluid retention.

This is not a complete list of side effects. Am J Cardiovasc Drugs ; 9 4: This offer is not valid for use by patients enrolled in Medicare, Medicaid, or other federal or state programs including any state pharmaceutical assistance programsor private indemnity or HMO insurance plans that reimburse you for the entire cost of your prescription drugs.

Allergan reserves the right to rescind, revoke, or amend this offer without notice. Renal clearance of nebivolol is decreased in patients with severe renal impairment. Maximum savings limits apply; patient out-of-pocket expense will vary.

The 5 most common adverse events were headache, fatigue, dizziness, diarrhea, and nausea.