Bergenia ligulata is a perennial herb with short, thick, fleshy and procumbent stems and very stout root stock. Leaves are ovate or round and cm long. Bergenia ligulata wall whole plant is used for kidney and bladder stones, urinary problems. (8,9,) It has been reported to exhibit various pharmacological. Pashanabheda- Bergenia ligulata (Wall.) Engl. is a small plant used in the treatment of renal calculi, retention of urine, wounds, diseases of the.
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Cardiotoxic, antidiuretic and CNS depressant action of B. However, DCM fraction may be explored as new phytopharmaceuticals drug in future.
Two different concentrations of each extract 5. Ethnomedicinal plants used by the people of Manang district, central Nepal. A total of 5. CRC Press Inc; The total reaction volume of solution was 1. The alcoholic extract elicited marked anti-bradykinin activity in-vivo and in-vitro but did not modify the response of 5-HT and acetylcholine on isolated guinea pig ileum. Antiviral activity of some plants used in Nepalese Traditional Medicine.
The oxalate crystal inhibition potential bergennia B.
Cortex consists of a narrow zone of parenchymatous cells containing a number of simple starch grains whereas most of cortical cells contain large rosette crystals of calcium oxalate CaC 2 O 4 and starch grains. Administration of ethylene glycol 0.
Results revealed that no marked damage in the hepatic structure and spleen was observed by using given concentration of mother extract and DCM fraction Supplementary Figure.
The dose is also a major concern for toxicity of plant extract, higher dose leading to toxicity of liver and spleen, but lgulata results supported the given dose for its therapeutic efficacy without any toxic effect.
Medicinal Plants of Himalaya. But a little amyloid deposition in red pulp and around white pulp was observed in both urolithiasis and drug treated groups but it was lesser in extract treated rat as compared to urolithiasis rat. Thirty two healthy volunteers and forty eight stone formers were selected for present study.
Bergenia Ligulata – Ayurvedic Herb
The contents of catechin, gallic acid, quercetin, and tannic acid are shown in Table 1. Limits for quality parameters Quality parameters for B. The yields of mother extract and its polarity based fractions were shown in Table 1. Head of Department, Ljgulata.
Bergenia ligulata – Asmabhedaka
Phytochemical evaluation and free radical scavenging properties of rhizome of Bergenia ciliate. Consumption of historical and current phytotherapeutic agents for urolithiasis: Handbook of Ayurvedic Medicinal Plants. Aqueous extract of B.
Dosage Forms and Safety Profile B. The analgesic activity was evaluated by using hydroalcoholic extract of rhizomes of B. Antiurolithic effect of Bergenia ligulata rhizome: View at Google Scholar B. Ethylene glycol in drinking water 0.
Consequently it was inferred that the extract was devoid of analgesic activity. Antihepatotoxic activity of bergenin, the major constituent of Mallotus japonicus on carbon tetrachloride-intoxicated hepatocytes.
Therefore it is assumed that bergenin exerted antihepatotoxicity against CCl 4 -induced cytotoxicity through glutathione-mediated detoxification as well as free radical suppressing activity. Analgesic activity The analgesic activity was evaluated by using hydroalcoholic extract of rhizomes of B. Some pharmacological studies on ethanolic extract of roots of Bergenia ligulata.
The fractions obtained were screened for in-vitro free radical scavenging activity using DPPH radical scavenging assay and nitric oxide scavenging assay This may be due to the presence bfrgenia antioxidant metabolites such as catechin, gallic acid, and quercetin which protect the kidney from oxidative injury by oxalate and crystal deposition [ 17 ].
These above changes induce the hyperoxaluria and succeeding crystal adherence and retention in renal tubules [ 26 ].