GATE PHYSICS BY SUREKHA TOMAR PDF

GATE PHYSICS BY SUREKHA TOMAR PDF

GATE Physics Solved Papers has 3 ratings and 0 reviews. Table of Contents Solved Paper Solved Paper Solved Paper Solved Paper paper Upkar LATEST EDITION. by Dr. Surekha Tomar by Anshul Gupta and Surekha Tomar GATE Physics Solved Papers. by Surekha. Read GATE Physics book reviews & author details and more at Free delivery on qualified by Dr. Surekha Tomar (Author). out of 5 stars 1.

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FERNANDO GUADALAJARA BOO CARDIOLOGIA PDF

Cardiologia [Jose Fernando Guadalajara Boo] on *FREE* shipping on qualifying offers. Acute Shock Dengue Myocarditis. Response. Jose Fernando Guadalajara-Boo a, a Training Program, Instituto Nacional de Cardiología Ignacio Chávez, Mexico. Pedro Bailón de la O · @ParisBailon. Futuro médico y buen amigo. pedrobailon. Joined November

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Function and mechanics of the left ventricle: Patel, 3 Natesa G. Received on May 13, ; Accepted on February 13, One of the most common indications in echocardiography is the evaluation of left ventricular function. The traditional measurement of ejection fraction is based upon tracing the left ventricular borders and calculating left ventricular volumes using geometric assumptions. However, regional myocardial function is more difficult to evaluate because it guadalajaea on visual assessment of endocardial motion and wall thickening.

Three dimensional speckle tracking 3DST has potential to be an ideal tool to assess not only global myocardial function but regional function through deformation, rotation, twist and untwisting parameters.

Besides, the inadvertent use of foreshortened views can raise its inaccuracy and low reproducibility. Alternatively, LV function can be assessed by Doppler techniques through the measurements of stroke volume using the continuity equation.

However, calculations of stroke volume by Doppler are dependent on the accuracy of left ventricle outflow tract measurement LVOT ; errors in the measurement, which cqrdiologia squared in the calculation of the LVOT area, limit the reliability of this parameter. Never the less, segmental wall motion has been more difficult to evaluate. Visual assessment has limited ability to detect more subtle changes in function and in timing of myocardial motion throughout systole and diastole.

Recently, echocardiographic modalities for objective quantification of global and regional function have been developed such as tissue Doppler and speckle tracking imaging. In this article, we review in a concise manner the methodology behind the development, usefulness, and shortcomings of these echocardiographic techniques. In cardiac muscle physiology, strain is a measurement of deformation representing shortening or stretching of the tissue or myocardial fibers. The strain value is dimensionless and can be represented as a fractional number or as a percentage change from an object’s original dimension Figure cardiologiz.

Cardiologia: Jose Fernando Guadalajara Boo: : Books

As the ventricle contracts, muscle shortens in the circumferential and longitudinal dimensions a negative strain and thickens in the radial and transversal direction a positive strain. Theoretically, strain values are not affected by the uniform translational motion of the heart and, as a consequence, they offer a clear advantage over velocity and displacement to assess the local functionality of the myocardium.

Completely passive segments can show motion relative to the transducer due to tethering, but without any deformation, making velocity fernand displacement information completely unreliable guadalajra the characterization of such regions. Strain rate SR is the rate at which deformation occurs, i.

By definition it is the temporal derivative of strain and expresses the rate of shortening or lengthening of a part of the heart. Currently, the principal strain vectors and their velocity derivatives Strain Rate can be assessed by tissue Doppler and speckle tracking echocardiography. Rather than assessing the rapid velocity blood pool as with conventional Doppler, uses filters to remove these signals to concentrate solely on the lower velocity myocardial motion.

Tissue Doppler imaging allows a quantitative analysis of the motion pattern of the cardiac walls. Several guadalajraa of investigators have demonstrated that strain analysis of a broader area is probably superior to tissue velocity data at one site and wall motion score for tracking local systolic function.

One of the most important clinical applications of TDI is the quantification of global LV systolic function; this can be done by measuring the myocardial peak systolic velocities of the mitral valve annulus at several locations and to derive an average of them. Gulati et al, reported an excellent correlation between systolic mitral annulus velocity Sm averaged from the apical views and LV ejection fraction.

Limitations of tissue doppler imaging: This implies that strain measurements from myocardial segments close to the left ventricle apical curvature cannot be reliably assessed by tissue Doppler imaging. Speckles are natural acoustic markers that occur as small and bright elements in conventional gray scale ultrasound images.

Understanding Heart Failure

The speckles are backscattered from structures smaller than a wavelength of ultrasound. These speckles are distributed all through the myocardium on the ultrasound image. In the speckle tracking methodology, a small area of the myocardium with its unique speckle pattern can be defined it is called “kernel” and tracked, following a search algorithm based on optical flow method, trying to recognize the feernando similar speckle pattern from one frame to another.

The algorithm searches for an area with the smallest difference in the total sum of pixel values, which is the smallest sum of absolute differences 39 Figure 6. For accurate speckle tracking, a high frame rate is important.

A high frame rate decreases the speckle change between frames, allowing better tracking.

The distance between selected speckles is measured within a predefined myocardial area as a function of time, and parameters of myocardial deformation can be calculated. Another important advantage by using the new technique is independence from insonation angle and cardiac translation. These values are not independent, one is positive wall thickening when the other is negative segment shortening in a normal heart.

The potential of 2D speckle tracking echocardiography has been investigated in numerous experimental and clinical studies for exploration of systolic and diastolic ventricular function, assessing ischemia, dyssynchrony, and other cardiac conditions, 46 some of which will be cited representatively in this review.

In initial studies, Becker et al, used 2D speckle tracking imaging huadalajara assess regional LV function. They compared a healthy group with a group of patients with previous myocardial infarction.

All subjects underwent guadlaajara magnetic resonance imaging CMRI. They found excellent correlation between the values obtained for peak radial and circumferential strains and the visual assessment of the MRI images. The sensitivity and specificity of this technique in the detection of dyssynergy were The results of these studies demonstrated concordance in the estimation of LV torsion between speckle tracking and tagged MRI and made the assessment of LV rotation and torsion available in clinical cardiology.

Left ventricular torsion is a critical component of cardiac biomechanics because it is important for normal ejection and suction and is a feature of the normal spread of excitation and connections among fibers.

The difference guuadalajara apex and base in the rotation angle is called twist and contributes significantly to LV ejection, in addition to myocardial shortening and thickening. It also has an important role in diastole since it contributes to diastolic suction in the early phases of ventricular filling in a process called untwist. Left ventricular torsion can be quantified by speckle tracking echocardiography. The interpretation of echocardiographic images requires a complex mental integration of different planes to understand anatomic structures and physiologic functions.

Three dimensional speckle tracking is a recent modality and its clinical application is currently being evaluated. Guaddalajara concluded that 3D speckle tracking “is a simple, feasible, and reproducible method to measure strain”.

They also reported differences in strain measurements and time to perform a complete 3DSTE analysis compared with 2D speckle tracking results. Currently 3D STE is being applied in the clinical field by several groups around the world.

Current limitations of speckle tracking echocardiography.

Further improvement of guadwlajara and temporal resolution of 3D STE is likely to overcome these drawbacks. As speckle tracking echocardiography evolves and becomes familiar, it will be mandatory to ensure standardization of terminology, steps in data acquisition, and optimal training to increase data accuracy and reproducibility.

A developing body of evidence suggests that guadalaajara of LV mechanics by tissue Doppler imaging and speckle tracking echocardiography offers valuable information in several clinical scenarios. Understanding such events could provide novel insight into the mechanisms of LV dysfunction, and may have the potential to identify subtle changes in LV mechanics in patients with subclinical myocardial dysfunction. With the advent of 3D echocardiography, three dimensional speckle tracking is emerging as a new tool that combines the usefulness of myocardial motion tracking with a better guadalzjara of the anatomic structures and physiologic function of the heart.

The evidence for the utility of this tool is growing and offers valuable fernaneo over TDI and two dimensional speckle tracking echocardiography, holding the promise for a better understanding of the mechanisms of LV dysfunction and tracking the impact of current and future therapies.

Recommendations for Chamber Quantification: J Am Soc Echocardiogr ; Recommendations for quantification of Doppler echocardiography: Eur Heart J ; J Am Coll Cardiol ; Pavlopoulos H, Nihoyannopoulos P. Strain and strain rate deformation parameters: Int J Cardiovasc Imaging ; Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain fernanco echocardiography in humans: Myocardial strain by Doppler echocardiography.

Validation of a new method to quantify regional myocardial function. Regional myocardial systolic function during acute myocardial ischemia assessed by strain Doppler echocardiography.

J Am Coll Cardiol Strain rate imaging by ultrasonography in the diagnosis of coronary artery disease. J Am Soc Echocardiogr ; Strain rate imaging during dobutamine stress echocardiography provides objective evidence of inducible ischemia. Use of peak systolic strain as an index of regional left ventricular function: Am J Bok ; Mitral annular descent velocity by tissue Doppler echocardiography as an index guxdalajara global left ventricular function.

Assessment of left ventricular systolic wall motion velocity with pulsed tissue Doppler imaging: Prognostic value of systolic mitral annular velocity measured with Doppler tissue imaging in patients with chronic heart failure caused by left ventricular systolic dysfunction.

Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function.

Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: Differentiation of constrictive pericarditis from restrictive cardiomyopathy: Differentiation of constrictive pericarditis from restrictive cardiomyopathy using mitral annular velocities by tissue Doppler echocardiography.

The use of TDI for the assessment of changes in myocardial structure and function in inherited cardiomyopathies. Eur J Echocardiogr ;6: Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy.

Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy. Echocardiographic characterization of cardiomyopathy in Friedreich’s ataxia with tissue Doppler echocardiographically derived myocardial velocity gradients. Doppler tissue imaging quantitates regional wall motion during myocardial ischemia and reperfusion. Detection of early abnormalities of left ventricular function by hemodynamic, echotissue Doppler imaging, and mitral Doppler flow techniques in patients with coronary artery disease and normal ejection fraction.

Quantitaive evaluation of the segmental left ventricular response to dobutamine stress by tissue Doppler echocardiography. Regonal diastolic function by pulsed Doppler myocardial mapping cardiologla the detection of left ventricular ischemia during pharmacologic stress testing.

Am Heart J ; A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging. Tissue synchronization imaging accurately measures left ventricular dyssynchrony and predicts response to cardiac resynchronization therapy.

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See all customer images. Read reviews that mention sound quality battery life earbuds bluetooth headphones stopped working great sound stay in my ears jaybird bluebuds sound great earphone tips highly recommend ear pieces much mannual sweat proof ear tips earbud good sound listening to music phone calls ear canal. Showing of 6, reviews. Top Reviews Most recent Top Reviews. There was a problem filtering reviews jayhird now. Standard Packaging Verified Purchase.

Let me start by saying I loved these jxybird. I’d tell everyone I knew that these were the best bluetooth headphones under bucks.

Until they stopped working. I reached out to Jaybird and was told I could get a replacement. Except I was sent another message by a different rep saying nothing could be done for me. Turns out lifetime warranty is only for the lifetime of the battery, which is two jaybidr. Two years to the day my left earbud stopped working and there was nothing Jaybird could do for me.

Each response from customer service took days to arrive and despite the first rep telling me I could get a replacement I was sternly told that my device was out of warranty and nothing could be done. Really disappointing to find out jaybbird two years of a “lifetime warranty” that the warranty doesn’t exist. I’ve gone through a few pairs of these now until I learned a trick to keep them going, more on this below. Overall they are great headphones, when used with the comply foam tips they stay in your ears really well.

The sound is decent for the size and they seem to work great with a broad range of devices. I bought them to use with my TomTom running watch, iphone, and ipad. All three work great. Where they really set themselves apart is with arguably the best support in the industry. These all operate in harsh environments with constant sweat and jarring. They are bound to fail at some point, what differentiates these from others is the no hassle exchanges.

Just call them up in within minutes you are setup to send yours in and get a new pair. I’ve never experienced customer service as helpful as they are. One critical trick I learned after going manyal a few pairs is these do not have current limiting built into the headphones manuql charging. You can overcharge the battery if you are not careful. The manual doesn’t explicitly say this but you should make sure your charger only supplies 1 Amp of charging current. This is the old style small square block apple charges supply 1 Amp if you still have one.

Using a charger with a higher current or leaving them connected overnight will hurt them. Most electronics have circuitry built in to prevent this, unfortunately these do not appear to have this and you can fry the battery.

During my last headphone exchange I mentioned to jaybirc support rep that I’d gone through a few and he seemed better informed than most and told me about this. Since I’ve changed to this charger and only left them long enough to turn the light green I haven’t had any failures. I’ve now got over sweaty running miles on the new ones with no issues. I bought these back in November

GS08 E C E C U PDF

being evaluated individually for execution on the batch system. In practice Computing on Grids and Supercomputers (MTAGS08), the grade of GS and below and Category. 2 is for participants in the grade of GS- .. Program Execu- tive Office Soldier officials discussed. GS GS GS GS GS GS P a y grade. Percentage of total. Our final proposal would be for new legislation to create an Execu-.

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Please type in a position! Please type in a location! Sign up Log in. Duties include, but are not limited to: Recommending discharge of patient when appropriate progress has or-has not been made based upon-the patient’s performance, behavior, and necessary changes made. Assisting in identifying outside resources available to the patient to help with other areas of their life.

Maintaining liaison with groups specific to the chemical and local Veterans Administration Hospitals. Keeping both the team, Clinical Psychologist and Program Manager appraised of standards.

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Rehabilitation Technician (Alcoholism) job

Monday – Friday, 7: This is not a virtual position. Not cc Financial Disclosure Report: Applicants who are current Federal employees and have held s GS grade any time in the past 52 weeks must x meet time-in-grade requirements by the closing date of this announcement. For a GS position you must have ee 52 weeks at the GS The grade may have been in any occupation, but must have been held in the Federal service. An SF that shows your time-in-grade eligibility must be submitted with your application materials.

You must have one year of specialized experience equivalent to at least the next lower grade Gs in the normal line of progression for gs0 occupation in the organization. Examples of specialized experience would typically include, but are not limited to: Experience that involved the observation of and assistance in the application of techniques relating to behavior, capacities, traits, interests, and activities of either humans or, under laboratory conditions, animals. Experience may have been gained in connection with a program of research or direct services in psychology that gave a practical understanding of some of the principles, methods, and techniques of psychology needed to assist professional psychologists.

Applicants may substitute education for the uu experience. To qualify based on education for this grade level you must have two full years of graduate education or a master’s degree which is directly related to the work of the position. OR, You will be rated on the following Competencies for this position: Ability to assess to progress success of patient development.

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Rehabilitation Technician (Alcoholism) job in North Chicago – Department of Veterans Affairs

This job was posted d Wed Oct 24 and expired on Sat Nov 24 Similar jobs in the area. This is a part-time 20 hours perweek position working in the evenings from 5pm-9pm Monday-Friday. No holidays, no weekends! Great for a student pursing a career in healthcare!

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EJERCICIO VLSM PDF

Transcript of Ejercicio VLSM para la casa. / Licencia clase C VLSM LAN1 LAN2 LAN3 LAN4 8. LAN5 8. LAN6 2. View Ejercicios de from SCINCE programmin at Utec Campus. Resolver los siguientes ejercicios de VLSM 1- Con la siguiente direccin IP. Subredes VLSM. Esta recopilación de calculadoras IP, online y para descargar, será de gran ayuda cuando estemos realizando ejercicios de subredes VLSM.

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It depends on your instructor creating your class. We recommend you to go thought all version if you are not clear. While you take online test with netacad. Each version have 1 to 10 different questions or more. After you review all questions, You should practice with our online test system by go to “Online Test” link below.

Red font color or gray highlights indicate text that appears in the Answer copy only. Based on a set of requirements, you will assign subnets and addressing, configure devices and verify connectivity.

You will subnet the network address [[DisplayNet]]. The network has the following requirements:. Complete the Subnet Tablelisting the subnet descriptions e.

Repeat until all addresses are listed. The correct answers for this table are variable depending on the scenario received. Refer to the Answer Notes at the end of these instructions for further information. Most of the IP addressing is already configured on this network.

Implement the following steps to complete the addressing configuration. However, you should be vlsj to ping every IP address listed in the Addressing Table.

VLSM Sample Problem #1

The majority of points are allocated to designing and documenting the addressing scheme. Implementation of the addresses in Packet Tracer is of minimal consideration. The following addressing tables represent the three possible addressing scenarios the student may get. Note that vlm Device column is independent of the addressing scheme.

For example, a student could receive the device names from Scenario 1 and the addressing scheme from Scenario 3. In addition, the three possible topologies are also independent of the device names and the addressing scheme click reset in the activity to see the different topologies.

VLSM Sample Problem #1

Posted on March 13, by Admin. Recommend From year to year, Cisco has updated many versions with difference questions.

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AP GODSE COMPUTER GRAPHICS PDF

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Computer Graphics – – Google Books

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KAPLEAU THREE PILLARS ZEN PDF

Roshi Philip Kapleau and the “Three Pillars of Zen”. Posted July 14, “If you fall into poverty, live that way without grumbling – then your poverty will not. THREE PILLARS O F ZEN. TICE. A ND E N L I G HTE N M E NT. [atio1lS; introductions & notes, by PHILIP KAPLEAU. BEACON PRESS. BOSTON. Through explorations of the three pillars of Zen–teaching, practice, and enlightenment–Roshi Philip Kapleau presents a comprehensive overview of the history.

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Zen Teaching, Zen Practice: It is generally agreed that D. While works such as these certainly brought Zen Buddhism to an eager and ravenous American public, they lacked one critical aspect: Teaching, Practice and Enlightenment.

Roshi Philip Kapleau – Rochester Zen Center

First published init has not been out of print ever pjllars, has been translated into ten languages and, perhaps most importantly, still inspires newcomers to take up the practice of Zen Buddhism. For many Zen students, it is still an essential inspirational reference work, one that urges the student to practice and practice hard to achieve kensho.

For many, if not most Zen students, just how difficult the practice is and how committed one must be came as a shock and, inevitably for some, a disappointment.

It is also necessary that we understand where and how Kapleau learned three Zen practice to better understand why he wrote and taught the way he did.

Kapleau returned to the United States but the taste of Zen was in his mouth and in he went back to Japan to settle his doubts. For three years ppillars trained under Harada Sogaku at Hosshinji and then furthered his practice under Yasutani Hakuun in Kamakura. He practiced with Yasutani for nearly ten years before returning to America as a Zen teacher.

So it is not surprising that Kapleau emphasized kensho in his book as both Harada and Yasutani were adamant that kensho and satori are the alpha and omega of Zen practice. But these were the teachers under whom Kapleau trained and learned his Zen. His account of his first sesshin in at the Rochester Zen Center will strike a kapelau with many who have had similar experiences of pain, uncertainty, suffering and desperation to do well.

It took another four years before his answer to Mu was accepted by Kapleau. Bodhin Kjolhede zwn shaken to his core by an encounter with U.

The Three Pillars of Zen by Roshi P. Kapleau | : Books

Although he had encountered the book earlier, it held no meaning for him and remained largely unread. The intensely personal narratives in Zen Teaching, Zen Practice, however, illustrate how valuable this book has been in setting people on the path of Zen. These two books will be seen as seminal texts in bringing Zen Buddhism to the West and, so far, no other writings have been as influential.

Zen Teaching, Zen Practice is not a fundamental text for Western Zen but it does serve as a useful counterpoint to the personal narratives that so influenced many beginners in The Three Pillars of Zen. All of this is part of the ongoing struggle to find the true meaning of Zen Buddhism in its inexorable march to the West.

Zen Teaching, Zen Practice, with its personal narratives of meeting Kapleau and his book is part of that ongoing struggle to create a Zen Buddhism relevant to our times, our needs, and our understanding. If you wish, you may make a small donation to help this site defray overhead costs.

BUPA HEALTHLINE PDF

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We use cookies to help us understand ease of use and relevance of content.

This ensures that we can give you the best experience on our website. If you continue, we’ll assume that you are happy to receive cookies for this purpose. Find out more about cookies. Bupa UK has over 22, employees supporting customers with their health, care and wellbeing needs, through a range of health and wellbeing services, care services and funding products.

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BOGAR 12000 PDF

am , Bogar book pdf free. PDF f fca20 Aavmker4 Aavmker4. Cons Terrible touchpad. Bogar book pdf free. Direct Link #1. – The above Tamil verses from bogar are easy to understand and extract about the intercourse of male and female. The verses say if.

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Bogar 12000 book

Please tell me about which verse in Bogar speaks about diseases related to human head and human nervous system and about the proposed cure for them. When i met a famous publisher at chennai, publishing spiritual books in tamil criticized on their bogaar part of Bogar “there is the major difference between the third part of bogar with another version which was published by his father around some 50 years back”. Also first part of preamble stages there is a hidden part verses published at palani town which is always used to handover to next disciples directly.

Thanks for the detailed info about these.

Bogar – eBook and Manual Free download

bogae You have mentioned some people in Madurai and palani had bogar book and it is not yet published right? Do you know it could you Mail me like whom to contact in Madurai or palani to get a copy?

Thillai, Your blog is interesting. Changes in palmleaf version during several centuries are possible when it is handed over down the generations. Authenticity is left to Bogar himself. If properly researched, books of siththar throw high potential news about all matters. Self experiment is useless and dangerous, it has to be tested under guidance of a guru. Few years ago I met and had darshan of guru Bogar who initiated me boogar write a book.

Recently I completed a book on guru and to be released next month vogar a chennai publisher. Infact, I have mentioned your blog also in my numerous reference list.

Bogar – Wikipedia

Very nice articles on your blog too. HiCan bogarr get Bogar Book in Chennaiif so drop a mail to arulsivan. Can I get Bogar’sbooks in chennai. Please send addresses of booksellers to my mail ID kssnathan yahoo. Tips for 120000 kind reply. Can I get yr mobile no so that I can contact you when I come to chennai? Sir Iam venugoal, doing research in siddha. I was told by my master that Bogar will be of great help.

Bogar 12000 in tamil

Could you please tell me where I can get this book. Please send details to my email ID: If you like to help me please drop your valuable information to my mail avidatham gmail.

Books regarding written by Agasthiyar, Bogar, Pulipaani and many Mahayogis. I have composed The whole of the Tamil language is the poet’s ally. The Tamil poets have had the added advantage of using a language medium, where the quality of sound and the impact of meaning seem to share a common ground as far as function are concerned. It deals mainly by using natural elements an eligible to make sophisticated science devices by transformation of one matter in to another matter through atoms.

Also some verses quoting aero dynamics.

Some of the doctors from hereditary siddha medicines at palani and some at Madurai and srilanka hold the copy of bogar with their own families carrying hereditarily and they recovered only most of the medicinal part of the poems due to practicing only siddha medicines in tamil. But Bhogar’s are “more readable” and published worldwide without any curses in the poems for ineligible. This have a part of the poems indicating factual secret map of irresistible consciousness and refined technical manual on Kundalini Yoga never ever written anywhere in the universe.

These seven-thousand verses flow in distinguished rhyme, a complex echoing of sounds whose meanings convey a flux of images, filled with a simple wisdom; others mysterious, encoded in the secret language of the mystic.

Among all his works, Bhogar composed the eighty-two verses presented in this work for all people without any curses in all bogar verses.

Any eligible person can read these poems for reference for medicine, herbs, alchemy and yogas. He has distilled the essence of Kundalini Yoga into a kind of guided meditation that presents the tradition’s set of symbols, in order to bogad for visualization and preparation for internally ready to makeup the final destination of this birth towards jeeva Samadhi.

As usual like other sidhar works such as this were also encoded in the secret hidden words to preserve the tradition without revealing the inner mysteries to the uninitiated or unqualified persons.

Bhogar have grown from sidhar tantric roots so it has been exposed in all his medicines, herbs and yoga explanation. He always quoted a language of symbol, myth, and metaphor to speak of the transformation of subtle energy which leads to the transformation of consciousness passing over along the poems.

Among all these thousand of nerves, a single nerve passing with many and lot of obstructions to the human brain and exactly create obstacles for individual human to practice particular yoga. No one have permission to expose more than this here for public including myself.

Mercury was viewed as the seminal seed of Shiva by all yogis. This particular type of rasamani, can use only in this material world who wants to increase life span with families. Cause the process of making mercury is artificial not from the raw natural rock. 120000 it describes some of siddhar passed urine on the metal and it turned immediately to gold also as reference. If crypted its start creates obstacles in life to disclose the secrets as per my self experience accordingly.

Posted by thillai raj at 1: Newer Post Older Post Home.

ESPRUE NO TROPICAL PDF

Tropical sprue is an acquired chronic diarrheal disorder of unclear etiology affecting residents of and visitors to tropical regions. Patients usually present with . English Spanish online dictionary Term Bank, translate words and terms with different pronunciation options. ESPRUE TROPICAL trastorno de diarrea crónica con mala absorción y deficiencia nutricional etiología desconocida regiones tropicales.

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Malabsorption is an important clinical problem both in visitors to the tropics and in native residents of tropical countries. Infections of the small intestine are the most important cause of tropical malabsorption. Protozoal infections cause malabsorption in immunocompetent hosts, but do so more commonly in the setting of immune deficiency.

Tropical malabsorption

In recent years, inflammatory bowel disease and coeliac disease have become major causes of malabsorption in the tropics. Sporadic tropical sprue is still an important cause of malabsorption in adults and in children in South Asia.

Investigations to exclude specific infective, immunological or mo causes are important before considering tropical sprue as tropial diagnosis. This tropicall briefly reviews the management of tropical sprue and presents an algorithm for its investigation and management. Malabsorption is an important clinical problem eslrue tropical countries, typically presenting with chronic diarrhoea, glossitis, weight loss and multiple nutritional deficiencies.

The aetiological profile of malabsorption in tropical countries often differs from that in temperate zones. A description in the ancient Indian medical treatise, Charaka samhitaof an illness characterised by chronic diarrhoea and weight loss and attributed to failure of the digestive system 1 suggests that the malabsorption syndrome was clinically recognised in eslrue tropics two millennia ago.

InWilliam Hillary described a malabsorption syndrome in expatriates tropcal in Barbados, 2 but the first case that he described may have been due to giardiasis rather than tropical sprue. Initially thought to be confined to visitors to the tropics, it became apparent in the early 20th century that indigenous residents of the tropics were afflicted with similar illnesses.

In the past two decades, the profile of malabsorption has changed in tropical countries, probably related to changes in hygiene and sanitation. This review considers tropical malabsorption as any syndrome of malabsorption that affects indigenous residents of tropical countries and also travellers visiting or residing in the tropics. Protozoal infections of the small intestine are particularly common in tropical countries and may be associated with malabsorption.

Protozoa are an important cause of traveller’s diarrhoea. Chronic diarrhoea and malabsorption are seen in a small proportion of infected people.

Giardia intestinalis is the protozoan parasite most commonly associated with malabsorption. Infection with this protozoan is common in the tropics and is often a cause of diarrhoeal illness in visitors to the tropics.

The presence of Espdue cysts in the stool indicates infection. In patients with diarrhoea, trophozoites in stool are usually present. Examination of at least three faecal specimens is recommended for optimal diagnosis of the infection. Other protozoa box 1 associated with malabsorption include Cryptosporidium parvumIsospora belliCyclospora cayetanensis and Microsporidia species Enterocytozoon bieneusi and Encephalitozoon intestinalis.

However, immunocompetent people also sometimes show prolonged symptoms. Before the AIDS epidemic, these protozoa were recognised as the causes of malabsorption mainly in patients with primary immunodeficiency syndromes such as common variable immunodeficiency, and were thus relatively uncommon. Since the advent of AIDS, protozoal infections have become seprue causes of tropical malabsorption, 2021 although they are now uncommon in the developed countries as a result of antiretroviral treatment.

For instance, C parvum is the most important diarrhoeal pathogen in Zaire and Uganda, whereas I belli is the most common pathogen causing chronic diarrhoea and malabsorption in south India. Algorithms for the management of malabsorption in the tropics require that HIV illness be first excluded by appropriate testing. Helminth infections are an occasional cause of tropical malabsorption. The most common of these are Strongyloides stercoralis and Capillaria philippinensis. Infection with S stercoralis is common in the tropics and may cause chronic diarrhoea and malabsorption in immunocompetent people.

Intermittent or persistent diarrhoea occurs, while steatorrhoea, anaemia and hypoproteinaemia are common. Treatment with thiabendazole, albendazole or ivermectin has been found to be effective. Intestinal tuberculosis is common in tropical countries. It may manifest with many clinical syndromes, including obstruction and malabsorption syndromes. Biochemical evidence of malabsorption can be found in many patients with intestinal tuberculosis, even though the patient may not present with a clinical diagnosis of the malabsorption syndrome.

The improvement in diarrhoea and malabsorption with antiretroviral treatment lends credence to this theory. Crohn’s disease is increasingly being diagnosed in tropical countries, 535455 and is an important differential diagnosis for tgopical. Malabsorption in Crohn’s disease may occur as a result of several factors. Terminal ileal resections can lead to vitamin B 12 deficiencies and bile salt malabsorption, whereas ileocaecal valve resections result in bacterial overgrowth causing malabsorption.

Common variable immunodeficiency occurs sporadically in residents of the tropics, and may present primarily as a malabsorption syndrome. The most common infection noted in these patients is with the protozoan G intestinalis.

Esprje protozoa may also colonise the small bowel and lead to malabsorption. These include I belliC parvum and microsporidia.

Tropical malabsorption

Selective immunoglobulin Ig A deficiency is less common and can be associated with a flat mucosa and giardiasis. Symptomatic chronic infection of the small bowel leads to malabsorption. Bacterial colonisation of the upper small bowel may also occur in some patients with primary immunodeficiency and cause malabsorption.

This is identified by quick response to treatment with tetracycline or other antibiotics. Immunoproliferative small intestinal disease IPSID was traditionally esprrue Mediterranean lymphoma but is not uncommon in the tropics. Patients present with chronic diarrhoea and malabsorption in the second and third decades of life. Abdominal pain may be a major complaint. Clubbing of the fingers is characteristic and abdominal masses may be palpated on physical examination.

Nutritional deficiencies and a marked weight loss are troical. Clonal proliferation may occur secondary to chronic trlpical recurrent infections of the intestine in childhood. Mucosal biopsy of the small intestine is characteristic and shows a dense cellular lymphoplasmacytic infiltrate in the lamina propria leading to effacement of the crypts.

Three stages of the disease are noted, ranging fsprue an apparently benign disease stage A to a clear lymphoma stage C. The disease progresses over variable periods of time to the development of lymphoplasmacytic and immunoblastic lymphoma. Staging of the disease by laparoscopy or laparotomy should precede chemotherapy or radiation therapy.

Recently, IPSID was shown to be associated with Campylobacter jejuni infection, trolical suggesting that this was one potential antigenic stimulus driving the uncontrolled proliferation of B cells. Incidence of IPSID is reducing in areas where it was previously prevalent, probably owing nno improving hygiene.

Idiopathic chronic calcific pancreatitis is endemic in several tropical regions including the Tropicql subcontinent and southern Africa. Symptoms typically develop in adolescence and the usual presentation is with recurrent abdominal pain attributable to pancreatitis.

In some patients, presentation is solely with features of chronic diarrhoea and malabsorption due to the exocrine pancreatic insufficiency.

Xylose absorption is usually normal in these patients, and faecal fat is grossly increased. Vitamin B 12 malabsorption may be noted in some people due to lack of pancreatic proteolytic activity and failure to cleave the R protein—vitamin B 12 complex.

Occasionally, endoscopic retrograde pancreatography or endoscopic ultrasonography is used to establish the diagnosis. Malabsorption can be treated by an oral dose of a pancreatic enzyme preparation such as Creon with every meal. The mucosa of the small intestine of residents of the tropics is structurally different from that of residents of temperate countries. The villi are shorter, crypts are more elongated and trppical are increased tropiccal of lymphocytes in the lamina propria.

Malabsorption of fat, vitamin B 12 and xylose, as well as increased mucosal permeability, has been noted in a large number of healthy residents of the tropics. Tropical enteropathy may represent an adaptation of the gut to frequent intestinal infection.

T cells possibly have a role in the development of enteropathy. Tropical sprue is an acquired disease of unknown aetiology, characterised by malabsorption, multiple nutritional deficiencies and mucosal abnormalities in the small bowel. The definition of the various clinical syndromes that are together termed tropical sprue is still controversial. Baker and Klipstein 78 suggested that the diagnosis of tropical sprue should be made only when there is tropival of two or more unrelated nutrient groups eg, fat and carbohydrateand after other known causes of malabsorption trkpical been excluded.

Tropical sprue – Wikipedia

The aetiology of tropical sprue remains unknown. The need for prolonged residence in the tropics and the response to antibiotics suggested that persistent intestinal infection was responsible. Bacterial contamination of the small bowel was described in returning expatriates who developed tropical sprue, 89 as well as in the indigenous population from several regions with endemic tropical sprue.

The issue of whether this bacterial colonisation could lead to tropical sprue in those with a genetic predisposition has not been considered, especially as earlier studies predated current understanding on innate immune responses in the gastrointestinal tract. In this study, 10 of 13 patients with sprue had aerobic bacteria in the small intestine in larger numbers median 3.

Similar slowing of small intestinal transit in coeliac disease can be reversed with gluten withdrawal. Viral particles resembling human enteric corona viruses have been identified in the stool of patients with tropical sprue. Coccidian parasites such as Cyclospora cayetanensis might have a role in the initiation of tropical sprue in some patients. Nutrient malabsorption in tropical sprue arises from involvement of both the proximal and distal small intestine.

Ultrastructural studies show degenerating cells in the crypts of the small intestine, suggesting stem cell damage. Bile acid malabsorption occurs as a result of terminal ileal involvement and may contribute to diarrhoea.

Colonic malabsorption of water and electrolytes contributes considerably to diarrhoea in patients with sprue, and may result from the action of unabsorbed bile acids and free unsaturated fatty acids. Villus atrophy, crypt elongation and inflammatory cell infiltration of the lamina propria can be seen. Images courtesy of Professor Anna Pulimood.

A typical patient with tropical sprue is an adult who presents with chronic diarrhoea, glossitis, bloating, prominent bowel sounds and weight loss. The signs of nutritional deficiency include pallor due to anaemia; angular stomatitis, cheilitis and glossitis due to vitamin B deficiency; and peripheral oedema and skin and hair changes secondary to hypoproteinaemia.

Rarely, vitamin A deficiency may manifest with night blindness and corneal xerosis, while vitamin B 12 deficiency leads to subacute combined degeneration of the spinal cord. In expatriates, the illness is heralded by acute diarrhoea associated with fever and malaise in the first week. A milder form of chronic diarrhoea, steatorrhoea and a marked weight loss follows this. Some patients may present solely with a specific nutritional deficiency such as megaloblastic anaemia or hyperpigmentation of the skin due to vitamin B 12 deficiency.

Fever, uncommon in Caribbean patients, has been noted in almost a quarter of patients from southern India.

Two abnormal tests in the appropriate setting are consistent with tropical sprue in the absence of other causes of malabsorption.

Quantitative stool fat estimation is the most reliable test of malabsorption in the tropics. Although this is useful to detect the increased faecal fat triglyceride in patients with chronic pancreatitis, Sudan stain is not sensitive in the diagnosis of tropical sprue, where the faecal fat is in the form of fatty acids rather than triglycerides.